Background

The objective of this study was to assess the efficacy of digital therapeutics for non-surgical and surgical weight loss. The non-surgical weight loss and weight maintenance assessment has been completed with compelling results, surgical weight loss assessment is in preparation.

Methods

This was a nonrandomized study of 391 participants, 59% of the participants were female and 41% were male. A digital therapeutic consisting of a special purpose of scale at the participants’ premise, a mobile app to deliver guidance, education, motivation, accountability, and community support, an AI agent, human coaches, and a dashboard to manage the participants was used. The knowledge base of the main guidance and education about nutrition and physical activities. The objective was to achieve 10% of weight loss in 24 weeks for the participants, divided into 6 weight buckets.

Results

For weight bucket 166-181 Kg, the weight loss (wl) was 14.81% with standard deviation, SD, = 7.3, for weight bucket 146-165Kg, wl 12.53%, SD = 6.8, for bucket 126-145 Kg, wl 14.50% with SD = 5.9, for bucket 106-125Kg, wl 14.0 % with SD = 5.2, for bucket 86-105Kg, wl 14.20% with SD = 4.4, for bucket 65-85 Kg, wl 13.29% with SD = 3.4.

Conclusions

An evidence-based, well-designed digital therapeutic with proper guidance through an AI agent and human coach, motivation, and accountability can achieve more than 10% weight loss. It’s a promising technological platform for post-op weight loss and maintenance.